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MINEXIN® TECHNOLOGY

Minexin Technology is Pharmology’s core innovation — designed to maximize absorption without compromising safety or purity.

MINEXIN® technology

MINEXIN® is a proprietary ingredient independently developed by Pharmology Global Co., Ltd. It is a next-generation bio solution that provides essential nutrients required for cells to restore their own regenerative capacity.
MINEXIN® Technology is based on the company’s proprietary library of 420 strains and natural materials database, and develops bio-based new materials through systematic screening and efficacy verification. It is a core platform technology for developing bio-based new materials.

The First Life Switch Cells Encounter

Proprietary Technology Developed by Pharmology Global

MINEXIN, a bio-based new material, is a platform material that combines the concepts of Mineral and Vaccine. It is characterized by converting minerals with low absorption rates in the body into low-molecular and organic forms through a probiotic fermentation process.

Verified Efficacy in Increasing Human Penetration and Absorption Rates

It is a new material that maximizes efficacy by dramatically improving bioavailability, which has been considered a limitation of conventional mineral materials.
Confocal Raman analysis demonstrated that, compared with purified water, it was delivered 1.63 times deeper, 4.82 times faster, and 4.82 times more into the skin layers.
MINEXIN is a bio-based new material that overcomes the limitations of delivery efficiency.

*Noninvasive Raman (Confocal Raman) Analysis:

A technology used to analyze how deeply substances are absorbed into the skin.

These results compare how much the applied ingredients are absorbed and diffused into the skin over time.
Blue indicates the degree of substance distribution, while yellow indicates areas where the substance is not distributed.

*No Treatment: Experimental group treated with purified water

Immediate Treatment: Immediately after applying MINEXIN®

30 Min Post Treatment: 30 minutes after applying MINEXIN®

Key Differentiators of MINEXIN®

(01)

Verified Efficacy in Increasing Human Penetration and Absorption Rates

(02)

Applied with Four Proprietary Patented Strains

(03)

Verified Through Four Internal Safety Tests

(04)

New Ingredient Registered in the International Cosmetic Ingredient Dictionary (ICID)

MINEXIN;α™ A Specialized Material for Skin Regeneration

(01) Minexin; α™
Essential biominerals that help improve the environment within skin cells, beneficial microbiome derived metabolites¹⁾, and phytoactive²⁾ gallic acid³⁾ containing nature’s defense mechanisms.

It deeply hydrates skin cells to prevent cellular dehydration and restructures the damaged skin barrier, activating the skin’s natural recovery mechanism.

1) Lactic Acid: Helps support natural moisturizing factor synthesis, inhibits melanin production, and maintains the skin’s mildly acidic environment.
Lipoteichoic Acid: Helps regulate skin immunity, suppress skin inflammation, and strengthen the skin barrier.
2) Phytoactive: Natural derived active ingredients with antioxidant, anti aging, moisturizing, and brightening benefits.
3) Gallic Acid: A powerful polyphenol antioxidant that helps protect skin cells and provides anti aging benefits.
(02) Active

01. Inflammation Regulation View All Work

MINEXIN;α™ helps relieve stress caused by inflammatory responses, supporting the reduction and defense of skin inflammation.

02. Barrier Strengthening View All Work

MINEXIN;α™ helps maintain a healthy skin barrier.

03. Enhanced Skin Moisturization View All Work

MINEXIN;α™ helps improve skin moisturization.

04. Skin Cell Wound Regeneration View All Work

MINEXIN;α™ may help maintain skin health and prevent aging by promoting skin damage repair and cell proliferation.

This study evaluated the cell regeneration efficacy of Minexin;α™ after inducing artificial damage to epidermal keratinocytes and dermal fibroblasts. Compared to the untreated control group, cell regeneration promoting effects of over 175% and 137% were confirmed, respectively.

*Untreated Group: Comparative control group with no treatment applied

05. *Anti Aging and *Antioxidant Effects View All Work

*Anti Aging: Benefits that help maintain healthy skin and body functions that naturally decline with age.

*Antioxidant: Benefits that help protect cells from harmful substances that cause skin and body aging and damage.

MINEXIN;α™ helps delay signs of skin aging.

Minexin;α™ promotes the expression of procollagen, a key gene involved in collagen production in dermal skin cells, while effectively inhibiting the expression of the MMP-1 gene, an enzyme that degrades collagen in the dermis. By strengthening the skin’s structural support and improving elasticity, it helps effectively delay signs of skin aging.

*Untreated Group: Comparative control group with no treatment applied

Control Group: Experimental group in which skin cells were exposed to ultraviolet rays to induce aging.

Minexin; HA™
(Minexin; HA™)

(01) Minexin; HA™
Deeply Absorbing and Long Lasting Moisture Recovery Power An Intensive Recovery Solution for Rapid Skin Environment Changes


A high moisturizing, high density hydration delivery and nourishment system combining MINEXIN;α™ with hyaluronic acid.
(02) Active

01. Intracellular Penetration View All Work

MINEXIN;HA™ has higher penetration into skin tissue than hyaluronic acid.

Untreated Group
Conventional HA
MINEXIN; HA™
Epidermal Cells
Non-treated group Keratinocyte 20μm
Hyaluronic acid Keratinocyte 20μm
MINEXIN HA Keratinocyte 20μm
Dermal Cells
Non-treated group Fibroblast 20μm
Hyaluronic acid Fibroblast 20μm
MINEXIN HA Fibroblast 20μm

Analysis of the absorption level after treating skin epidermal and dermal cells with MINEXIN;HA™ showed that it has 290% greater penetration into epidermal cells and 830% greater penetration into dermal cells compared to conventional hyaluronic acid.

The intensity of the green fluorescence indicates the degree of hyaluronic acid distribution within the cells.

Hyaluronic Acid: A representative ingredient known for its skin moisturizing benefits.

Untreated Group: Comparative control group with no treatment applied.

02. Skin Moisturization View All Work

MINEXIN;HA™ provides excellent moisturization within skin tissue.

Hyaluronic acid skin moisture retention
MINEXIN HA skin moisture retention
Conventional HA
MINEXIN;HA™

Minexin-HA™ shows 145% higher moisture retention within skin tissue compared to treatment with hyaluronic acid alone.

*The intensity of the green fluorescence indicates the level of moisture retention.

Hyaluronic Acid: A representative ingredient known for its skin moisturizing benefits.

03. Prevention of Skin Moisture Loss View All Work

MINEXIN;HA™ helps maintain and protect skin moisture.

04. Improvement of Dermal Density View All Work

MINEXIN;HA™ helps improve skin elasticity more effectively than hyaluronic acid.

Hyaluronic acid
MINEXIN; HA™
Hyaluronic acid skin moisture retention
MINEXIN HA skin moisture retention

Improvement Effect of MINEXIN;HA on Dermal Cell Density in the Skin

Minexin; β™
A Specialized Material for Scalp and Hair Strengthening

(01) Minexin; β™

Essential biominerals deliver energy deep into the scalp, microbiome derived metabolites¹⁾ help maintain a healthy scalp balance, and marine derived amino acids²⁾ provide vitality and resilience to the scalp.

By promoting the proliferation of dermal papilla cells and improving the scalp environment

It is a functional bio based advanced material that strengthens the foundation for healthy hair growth.

1) Bacteriocin: A natural antimicrobial peptide that helps protect beneficial scalp bacteria and relieve scalp troubles.
EPS (Exopolysaccharides): Helps form a moisturizing barrier on the scalp, block external irritation, and strengthen the scalp’s natural resilience.
2) Marine Derived Amino Acids: Mycosporine-like Amino Acids that help protect against ultraviolet rays and activate antioxidant cells.
(02) Active

01. Dermal Papilla Cell Proliferation View All Work

MINEXIN;β™ helps support hair growth and maintain healthy hair follicles.

DHT

DHT group

Minoxidil

MINOXIDIL group

MINEXIN; β

MINEXIN beta group

02. Scalp Cell Proliferation View All Work

MINEXIN;β™ helps protect the scalp and support hair growth.

DHT

DHT

Minoxidil

Minoxidil

MINEXIN;β

MINEXIN beta

03. Anti Inflammatory and Dandruff Causing Bacteria Inhibition View All Work

MINEXIN;β™ helps soothe the scalp.

04. Relief of Scalp Itching View All Work

MINEXIN;β™ helps relieve scalp itching.

05. Increased Hair Density View All Work

Products containing MINEXIN;β™ help prevent hair loss.

Minexin; S™
A Material for Inflammation Regulation and Circulation Improvement

(01) Minexin; S™
A complex repair solution that normalizes cellular function by relieving inflammation and improving dehydration, while promoting circulation and recovery.
(02) Active

01. Inflammation Suppression View All Work

MINEXIN;S™ helps enhance immunity by suppressing inflammatory responses.

02. Improved Blood Circulation View All Work

MINEXIN;S™ helps improve blood flow circulation.

03. Tissue Recovery View All Work

MINEXIN;S™ helps normalize contracted fascia and damaged ligaments.

Before

Before ultrasound image

After

After ultrasound image

Before

Before fiber structure image

After

After fiber structure image

These results were compared through ultrasound imaging after injecting MINEXIN;S™ into contracted fascia and damaged ligaments.

*Before: Before using MINEXIN;S™
After: After using MINEXIN;S™

01

MINEXIN;α™

  • Relief of Cellular Dehydration
  • Relief of Inflammation
  • Skin Barrier Strengthening
  • Skin Regeneration
  • Anti Aging Care
02

MINEXIN;HA™

  • Relief of Cellular Dehydration
  • Cell Nutrient Supply
  • Skin Moisturization
03

MINEXIN;β™

  • Hair Follicle Cell Activation
  • Relief of Scalp Inflammation
  • Hair Root Strengthening
  • Strengthening of the Hair Growth Cycle
  • Hair Loss Relief
04

MINEXIN;S™

  • Tissue Inflammation Regulation
  • Improved Blood Circulation
  • Relief of Cellular Dehydration
  • Cell Regeneration

Minexin; α™

Minexin; HA™

Minexin; β™

Minexin; S™

Minexin; α™

Minexin; HA™

Minexin; β™

Minexin; S™

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