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Advancing

Delivery Engineering

Technology

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Advancing

Delivery Engineering

Technology

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Advancing

Delivery Engineering

Technology

Stability Engineering
Penetration Engineering
Targeted Delivery

DELIVERY ENGINEERING TECHNOLOGY

Delivery Engineering Technology That Enhances the Value of High-Functionality Bio-Materials

We research delivery engineering technologies to enhance the stability of active ingredients and maximize absorption efficiency and delivery performance. Through formulation design and advanced delivery systems, we provide solutions that enable the efficacy of bio-materials to be expressed more effectively.

Active Ingredient Stabilization Technology

This technology enhances stability to protect bioactive ingredients from external environmental factors such as heat, light, and oxidation.

Absorption and Delivery Optimization Technology

This technology improves absorption and delivery efficiency so that active ingredients can be more effectively delivered to the areas where they are needed.

Delivery Performance Engineering

Introducing the Core Elements of Delivery Engineering Technology

01 Stability Engineering - Stabilization Technology That Suppresses Active Ingredient Degradation and Maintains Activity
This technology enhances stability to prevent active ingredients from being easily degraded or losing activity due to external environmental factors such as oxidation, heat, and light. It is designed to keep ingredients uniform and stable within the formulation, while supporting the maintenance of quality and activity during long-term storage. It also protects sensitive active ingredients through encapsulation and complexation technologies, continuously securing ingredient stability under various environmental conditions.
Because the skin has a strong barrier structure that limits the penetration of external substances, precise absorption design is required for active ingredients to reach the areas where they are needed. Penetration Engineering is a technology that optimizes formulations and structures according to the characteristics of the skin barrier, and improves absorption efficiency by controlling the physicochemical properties of active ingredients. In particular, by designing delivery pathways that consider the balance between hydrophilic and lipophilic properties, it enhances diffusion and delivery efficiency within the skin, creating a foundation for active ingredients to work more effectively.
To maximize the efficacy of active ingredients, it is important not only to enhance absorption but also to deliver them precisely to the required cells and tissues. Targeted Delivery Engineering is a technology that applies intercellular signaling mechanisms using EV-based delivery systems and improves delivery accuracy to specific tissues and cells. This enables active ingredients to reach target sites more efficiently and maximizes intracellular action efficiency, increasing the application value of functional materials.
EV Platform Engineering

EV Platform Technology Using Intercellular Delivery Mechanisms

01 Hybrid EV - Technology That Secures Both Delivery Efficiency and Functional Expandability through the Fusion of Dual Carriers
Hybrid EV is a next-generation delivery platform technology that combines the advantages of different carriers to enhance both delivery efficiency and functionality. Based on membrane fusion between liposomes and probiotic EVs, or between plant EVs and probiotic EVs, it is designed to complementarily utilize the unique properties of each carrier. Through this, it can overcome the limitations of conventional carriers while loading high concentrations of minerals and various active ingredients, enabling the development of customized functional materials through quantitative active ingredient loading.
Surface Functionalization is a technology that functionally designs the surface of carriers to enhance selectivity for specific cells or tissues. By attaching cell or tissue-targeting peptides to the EV surface, target specificity can be precisely controlled, thereby further improving delivery efficiency to the desired site. In addition, based on peptide structures, target-specific functionality can be expanded while maintaining surface stability, allowing it to develop into a flexible delivery platform for various applications.
Bioprocess Optimization Design is a technology that systematically optimizes the production processes of carriers and active ingredients to secure yield, quality, and bioactivity simultaneously. Through multivariate process design based on RSM and CCD, key variables such as media composition, fermentation conditions, and EV isolation processes are identified, and interactions between variables are quantitatively analyzed. Based on this, production yield can be increased while reproducibly maintaining bioactivity, establishing a stable manufacturing foundation that considers mass production and scale-up.

pharmology global

Proposing New Possibilities for Functional Bio-Materials

Contact Us
We complete the skin’s natural recovery with pharmaceutical standard biotechnology.
lab@pharmologyglobal.com
  • Company Pharmology Global Co., Ltd.
  • Representative Jungeun Yang
  • Business Registration No. 425-88-03067
  • Address Room 905, Ace Gwanggyo Tower 2, 91, Changnyong-daero 256beon-gil, Yeongtong-gu, Suwon-si, Gyeonggi-do, Republic of Korea
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